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Book

Histoplasmosis

Sami M. Akram  1 , Janak Koirala  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Histoplasmosis

Sami M. Akram et al.
Free Books & Documents

Excerpt

Histoplasma capsulatum (Hc) is a dimorphic fungus present worldwide in pockets of endemicity particularly associated with river valleys. The endemic regions in the United States are Ohio and Mississippi river valleys as well as southeastern states. It is a soil-based fungus, and when it is disturbed, the conidia become airborne and can be inhaled. Often the infections are asymptomatic, but a granulomatous inflammation results in pulmonary disease akin to pulmonary tuberculosis. In immunocompromised patients, histoplasmosis can become disseminated and lead to considerable morbidity and mortality.[1]

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Conflict of interest statement

Disclosure: Sami Akram declares no relevant financial relationships with ineligible companies.

Disclosure: Janak Koirala declares no relevant financial relationships with ineligible companies.

References

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