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Case Reports
. 2017 Aug 16:4:e100.
doi: 10.14309/crj.2017.100. eCollection 2017.

AA Amylodisis Associated with Jugular Paraganglioma as a Rare Cause of Chronic Diarrhea

José M Olmos-Martínez  1 , Remigio Mazorra  2 , Cristina Magadán  3 , Luis Martín  1 , Javier Crespo  1
Affiliations
Case Reports

AA Amylodisis Associated with Jugular Paraganglioma as a Rare Cause of Chronic Diarrhea

José M Olmos-Martínez et al. ACG Case Rep J. .

Abstract

We report a case of a 64-year-old man with chronic diarrhea who was diagnosed of a systemic reactive (AA) amyloidosis associated with a jugular paraganglioma. This neoplasm was diagnosed 30 years previously and it was not removed after extensive evaluation by a multidisciplinary team. Chronic inflammatory diseases are the major cause of AA amyloidosis. However, benign tumors, such as jugular paragangliomas, are considered to be one of the tumors that can result in AA amyloidosis.

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Figures

Figure 1
Figure 1
Magnetic resonance imaging of a 9-cm jugular paraganglioma invading the skull base, carotid vessels, and the mastoid part of the temporal bone.
Figure 2
Figure 2
Submucosal deposits of eosinophilic material in extracellular spaces and on the wall of the vessels, with apple-green birefringence after Congo red stain.
Figure 3
Figure 3
Immunohistochemical staining of the vessel walls positive for AA-type amyloid deposits.
See this image and copyright information in PMC

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