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Review
. 2018 Apr;115(4):302-308.
doi: 10.1007/s00347-017-0560-5.

[CyberKnife®: new treatment option for uveal melanoma]

[Article in German]
J M Mor  1 , R Semrau  2 , W Baus  2 , K R Koch  1 , F Schaub  1 , C Cursiefen  1 , S Marnitz  2   3 , L M Heindl  4   5
Affiliations
Review

[CyberKnife®: new treatment option for uveal melanoma]

[Article in German]
J M Mor et al. Ophthalmologe. 2018 Apr.

Abstract

Background: CyberKnife® stereotactic radiosurgery is a new treatment option for uveal melanoma.

Objective: This review outlines the technique of robot-assisted CyberKnife® therapy, as well as the pros and cons in the treatment of uveal melanoma.

Methods: The study provides a PubMed literature review and own preliminary clinical experiences.

Results: CyberKnife® therapy for choroidal and ciliary body melanomas shows comparable results concerning local tumor control and overall survival matching those of conventional therapies. With only low complication rates, a high level of quality of life can be conserved by possible preservation of visual acuity as well as the ocular globe.

Conclusion: Stereotactic radiosurgery using CyberKnife® seems to be an efficient and safe therapeutic option for malignant melanomas affecting the choroid and ciliary body. Comparative studies with conventional radiation strategies are now a high priority.

Keywords: Brachytherapy; CyberKnife®; Stereotactic radiosurgery; Teletherapy; Uveal melanoma.

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References

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