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Review
. 2017;30(3):436-441.

[Effects of saffron (Crocus sativus l. iridaceae) on blood level of follicle-stimulating hormone, and number and dynamics of body weight of offspring in female rats]

[Article in Russian]
Affiliations
  • PMID: 28849891
Review

[Effects of saffron (Crocus sativus l. iridaceae) on blood level of follicle-stimulating hormone, and number and dynamics of body weight of offspring in female rats]

[Article in Russian]
U F Hashimova et al. Adv Gerontol. 2017.

Abstract

This paper reviews the effects of saffron Сrocus sativus L. Iridaceae which grow in Azerbaijan on blood level of follicle-stimulating hormone (FSH), and number and dynamics of body weight of offspring in female rats. The findings indicated that the per os administration of alcoholic extract of saffron was able to decrease the FSH levels in blood of the 12-month-old rats as compared to that in the control group, involving the animals of the same age which have not received the saffron extract, and was close to the FSH levels reported for the 6-month rats. There was also an increase in number and body weight of pups from rats receiving the saffron extract prior to pairing with the intact males.

Изучено влияние экстракта из рылец шафрана, произрастающего в Азербайджане, на уровень фолликулостимулирующего гормона (ФСГ) в крови у крыс-самок, а также на количество и динамику массы тела у их потомства. В ходе экспериментов установлено, что под влиянием экстракта шафрана у 12-месячных животных уровень ФСГ в крови уменьшается по сравнению с аналогичным показателем у животных того же возраста, не получавших экстракт, и приближается к уровню, который отмечается у 6-месячных животных. Отмечено также достоверное увеличение количества потомства от самок, получавших экстракт шафрана в период до спаривания с интактными самцами, и весового показателя развития их крысят.

Keywords: dynamics of pubs body weight; female-rats; follicle-stimulating hormone; number of offspring; phytogeroprotector; pups of 1-2 month age; saffron extract.

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