Pancreatitis: Preventing catastrophic haemorrhage
- PMID: 28852306
- PMCID: PMC5558110
- DOI: 10.3748/wjg.v23.i30.5460
Pancreatitis: Preventing catastrophic haemorrhage
Abstract
Pancreatitis represents nearly 3% of acute admissions to general surgery in United Kingdom hospitals and has a mortality of around 1%-7% which increases to around 10%-18% in patients with severe pancreatitis. Patients at greatest risk were those identified to have infected pancreatic necrosis and/or organ failure. This review seeks to highlight the potential vascular complications associated with pancreatitis that despite being relatively uncommon are associated with mortality in the region of 34%-52%. We examine the current evidence base to determine the most appropriate method by which to image and treat pseudo-aneurysms that arise as the result of acute and chronic inflammation of pancreas. We identify how early recognition of the presence of a pseudo-aneurysm can facilitate expedited care in an expert centre of a complex pathology that may require angiographic, percutaneous, endoscopic or surgical intervention to prevent catastrophic haemorrhage.
Keywords: Complication of pancreatitis; Haemorrhage; Pancreatitis; Pseudoaneurysm; Splenicartery.
Conflict of interest statement
Conflict-of-interest statement: None of the authors has any potential conflicting financial interests relevant to this article.
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References
-
- McLean R, Jones M, Kanakala V, Dixon S, McCallum I. PWE-204 Acute pancreatitis: incidence, management and outcome trends over 15 years. Gut. 2015;64:A301–A302.
-
- Hamada S, Masamune A, Kikuta K, Hirota M, Tsuji I, Shimosegawa T; Research Committee of Intractable Diseases of the Pancreas. Nationwide epidemiological survey of acute pancreatitis in Japan. Pancreas. 2014;43:1244–1248. - PubMed
-
- Shen HN, Lu CL, Li CY. Epidemiology of first-attack acute pancreatitis in Taiwan from 2000 through 2009: a nationwide population-based study. Pancreas. 2012;41:696–702. - PubMed
-
- Yadav D, Whitcomb DC. The role of alcohol and smoking in pancreatitis. Nat Rev Gastroenterol Hepatol. 2010;7:131–145. - PubMed
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