Temperature-dependent transcriptional regulation of expression of fimbriae in an Escherichia coli strain isolated from a child with severe enteritis
- PMID: 2885277
- PMCID: PMC260589
- DOI: 10.1128/iai.55.7.1734-1736.1987
Temperature-dependent transcriptional regulation of expression of fimbriae in an Escherichia coli strain isolated from a child with severe enteritis
Abstract
Escherichia coli 469-3 synthesizes fibrillar fimbriae at 37 degrees C, but not at 18 degrees C, which promote its adherence to human colonocytes. RNA homologous with a cloned fragment of the strain 469-3 chromosome necessary for normal expression of fimbriae was virtually undetectable in bacteria grown at 18 degrees C, indicating that environmental temperature affects expression by regulating transcription.
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