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Meta-Analysis
. 2017 Aug 30;6(9):e005983.
doi: 10.1161/JAHA.117.005983.

Role of Total, Red, Processed, and White Meat Consumption in Stroke Incidence and Mortality: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

Kyuwoong Kim  1 , Junghyeon Hyeon  2 , Sang Ah Lee  3 , Sung Ok Kwon  3 , Hyejin Lee  2   4 , NaNa Keum  5 , Jong-Koo Lee  6 , Sang Min Park  7   2
Affiliations
Meta-Analysis

Role of Total, Red, Processed, and White Meat Consumption in Stroke Incidence and Mortality: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

Kyuwoong Kim et al. J Am Heart Assoc. .

Abstract

Background: Previous meta-analyses on meat intake and risk of stroke did not report the effect of white meat (poultry meat, excluding fish) and did not examine stroke incidence and mortality separately. We aimed to investigate the relationship of total (red and processed meat), red (unprocessed or fresh red meat), and processed (processed red meat) consumption along with white meat on risk of stroke incidence and mortality.

Methods and results: Articles were identified from databases and reference lists of relevant studies up to October 28, 2016. We selected prospective cohort studies on meat consumption specified by types of meat and stroke incidence and mortality reporting relative risks and 95% confidence intervals. The pooled relative risk was estimated using the random-effects model. Based on the inclusion criteria, 10 articles containing 15 studies (5 articles with 7 studies including 9522 cases of stroke incidence and 254 742 participants and 5 articles with 8 studies containing 12 999 cases of stroke mortality and 487 150 participants) were selected for quantitative synthesis. The pooled relative risks (95% confidence intervals) for total, red, processed and white meat consumption and total stroke incidence were 1.18 (1.09-1.28), 1.11 (1.03-1.20), 1.17 (1.08-1.25), and 0.87 (0.78-0.97), respectively. Total meat consumption (0.97 [0.85-1.11]) and red meat consumption 0.87 (0.64-1.18) were not significantly associated with stroke-related death.

Conclusions: The relationship between meat intake and risk of stroke may differ by type of meat. Recommendations for replacing proportions of red and processed meats to white meat for the prevention of stroke may be considered in clinical practice.

Keywords: cerebrovascular accident; cerebrovascular infarction; cerebrovascular ischemia; meat consumption.

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Figures

Figure 1
Figure 1
Flow diagram for identification and study selection. PM indicates processed meat; RM, red meat; TM, total meat; WM, white meat. The numbers in parentheses refer to the number of comparisons within the studies according to types of meat.
Figure 2
Figure 2
Relative risk (RR) ratios of total, red, processed, and white meat consumption and total incidence in stroke (highest vs lowest category). Weights are assigned from random‐effects model. CI indicates confidence interval; F, female; M, male.
Figure 3
Figure 3
Total and red meat consumption and relative risk (RR) of stroke mortality (highest vs lowest category). Weights are assigned from random‐effects model. CI indicates confidence interval; F, female; M, male.
See this image and copyright information in PMC

References

    1. Bonita R, Mendis S, Truelsen T, Bogousslavsky J, Toole J, Yatsu F. The global stroke initiative. Lancet Neurol. 2004;3:391–393. - PubMed
    1. Adamson J, Beswick A, Ebrahim S. Is stroke the most common cause of disability? J Stroke Cerebrovasc Dis. 2004;13:171–177. - PubMed
    1. Feigin VL, Forouzanfar MH, Krishnamurthi R, Mensah GA, Connor M, Bennett DA, Moran AE, Sacco RL, Anderson L, Truelsen T. Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet. 2014;383:245–255. - PMC - PubMed
    1. Johnston SC, Mendis S, Mathers CD. Global variation in stroke burden and mortality: estimates from monitoring, surveillance, and modelling. Lancet Neurol. 2009;8:345–354. - PubMed
    1. He FJ, Nowson CA, MacGregor GA. Fruit and vegetable consumption and stroke: meta‐analysis of cohort studies. Lancet. 2006;367:320–326. - PubMed