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Review
. 2018 Apr;57(4):531-541.
doi: 10.1002/mus.25949. Epub 2017 Sep 23.

The adaptive response of skeletal muscle: What is the evidence?

Stanley Salmons  1
Affiliations
Review

The adaptive response of skeletal muscle: What is the evidence?

Stanley Salmons. Muscle Nerve. 2018 Apr.

Abstract

Adult skeletal muscle is capable of adapting its properties in response to changing functional demands. This now sounds like a statement of the obvious, and many people assume it has always been this way. A mere 40 years ago, however, the picture was entirely different. In this Review and personal memoir, I outline the scientific context in which the theory was generated, the objections to it from entrenched opinion, and the way those objections were progressively met. The material should be of some historical interest, but, more importantly, it collects together the full range of evidence on which the current paradigm is based. Muscle Nerve 57: 531-541, 2018.

Keywords: adaptive; history; hypothesis; plasticity; stimulation; transformation; trophic.

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