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Review
. 2018 Oct-Nov;20(9-10):610-614.
doi: 10.1016/j.micinf.2017.08.003. Epub 2017 Aug 30.

HIV-1 mutates to adapt in fluxing environments

Masako Nomaguchi  1 , Naoya Doi  1 , Takaaki Koma  1 , Akio Adachi  2
Affiliations
Free article
Review

HIV-1 mutates to adapt in fluxing environments

Masako Nomaguchi et al. Microbes Infect. 2018 Oct-Nov.
Free article

Abstract

Human immunodeficiency virus type 1 (HIV-1) is specifically adapted for replication, persistence, transmission, and survival in humans. HIV-1 is highly mutable in nature, and well responds to a variety of environmental pressures by altering its genome sequences. In this review, we have described experimental evidence that demonstrates this phantasmagoric property of HIV-1.

Keywords: Adaptive mutations; Escape mutations; HIV-1; Sequence variations.

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