Letter to the editor: BET inhibitors might target innate inflammatory and profibrotic signaling networks in COPD

Jing Du¹, Yong Han^{2

3

4}

Affiliations

¹ Department of Gastroenterology, Zhejiang Provincial People's Hospital, Zhejiang, People's Republic of China.
² Clinical Research Institute, Zhejiang Provincial People's Hospital, Zhejiang, People's Republic of China; hanyine@gmail.com.
³ People's Hospital of Hangzhou Medical College, Zhejiang, People's Republic of China; and.
⁴ Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Zhejiang, People's Republic of China.

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Comment

Jing Du et al. Am J Physiol Lung Cell Mol Physiol. 2017.

Free article

. 2017 Sep 1;313(3):L648-L649.

doi: 10.1152/ajplung.00246.2017.

Jing Du¹, Yong Han^{2

3

4}

¹ Department of Gastroenterology, Zhejiang Provincial People's Hospital, Zhejiang, People's Republic of China.
² Clinical Research Institute, Zhejiang Provincial People's Hospital, Zhejiang, People's Republic of China; hanyine@gmail.com.
³ People's Hospital of Hangzhou Medical College, Zhejiang, People's Republic of China; and.
⁴ Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Zhejiang, People's Republic of China.

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BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure.
Duan Q, McMahon S, Anand P, Shah H, Thomas S, Salunga HT, Huang Y, Zhang R, Sahadevan A, Lemieux ME, Brown JD, Srivastava D, Bradner JE, McKinsey TA, Haldar SM. Duan Q, et al. Sci Transl Med. 2017 May 17;9(390):eaah5084. doi: 10.1126/scitranslmed.aah5084. Sci Transl Med. 2017. PMID: 28515341 Free PMC article.