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. 2018 Jan;141(1):419-423.e5.
doi: 10.1016/j.jaci.2017.07.029. Epub 2017 Sep 1.

Allergen sensitization in a birth cohort at midchildhood: Focus on food component IgE and IgG4 responses

Jeffrey M Wilson  1 , Lisa Workman  1 , Alexander J Schuyler  1 , Sheryl L Rifas-Shiman  2 , Emily C McGowan  1 , Emily Oken  2 , Diane R Gold  3 , Robert G Hamilton  4 , Thomas A E Platts-Mills  5
Affiliations

Allergen sensitization in a birth cohort at midchildhood: Focus on food component IgE and IgG4 responses

Jeffrey M Wilson et al. J Allergy Clin Immunol. 2018 Jan.
No abstract available

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Figures

Fig 1
Fig 1
A, IgE sensitization to inhalant and food allergen extracts in 6-10 year olds (n = 616) as measured by ImmunoCAP. B, Comparison of IgE results from microchip assay with results from the extract assay. C, Comparison of food-specific components with ImmunoCAP singleplex and ISAC. Class sensitization (on x-axis) was determined by extract testing and statistics reflect the χ2 test with Yates correction.
Fig 2
Fig 2
A, Representative results of samples that were tested for IgE and IgG4 to cow's milk and peanut components by ImmunoCAP, and for IgE to components by ISAC. B, Specific IgG4 levels from samples that were positive to the component-relevant food specific IgE by extract testing where threshold of detection of specific IgG4 was 0.07 μg/ml. Data represents geometric means where error bars are the 95% CI. Values less than the threshold of detection are shown below the dotted line and are not included in the geometric mean. C, Milk (n=20) and peanut (n=23)-specific components were plotted for IgE and IgG4. Where IgE and IgG4 were less than the detection limit they were depicted with the values 0.25 kU/L and 0.04 μg/mL, respectively.
See this image and copyright information in PMC

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