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. 2017 Sep 4;22(9):1473.
doi: 10.3390/molecules22091473.

Medicinal Plants Based Products Tested on Pathogens Isolated from Mastitis Milk

Claudia Pașca  1 , Liviu Mărghitaș  2 , Daniel Dezmirean  3 , Otilia Bobiș  4 , Victorița Bonta  5 , Flore Chirilă  6 , Ioana Matei  7 , Nicodim Fiț  8
Affiliations

Medicinal Plants Based Products Tested on Pathogens Isolated from Mastitis Milk

Claudia Pașca et al. Molecules. .

Abstract

Bovine mastitis a major disease that is commonly associated with bacterial infection. The common treatment is with antibiotics administered intramammary into infected quarters of the udder. The excessive use of antibiotics leads to multidrug resistance and associated risks for human health. In this context, the search for alternative drugs based on plants has become a priority in livestock medicine. These products have a low manufacturing cost and no reports of antimicrobial resistance to these have been documented. In this context, the main objective of this study was to determine the antimicrobial effect of extracts and products of several indigenous, or acclimatized plants on pathogens isolated from bovine mastitis. A total of eleven plant alcoholic extracts and eight plant-derived products were tested against 32 microorganisms isolated from milk. The obtained results have shown an inhibition of bacterial growth for all tested plants, with better results for Everniaprunastri, Artemisiaabsinthium, and Lavandulaangustifolia. Moreover, E.prunastri, Populus nigra, and L. angustifolia presented small averages of minimum inhibitory and bactericidal concentrations. Among the plant-derived products, three out of eight have shown a strong anti-microbial effect comparable with the effect of florfenicol and enrofloxacin, and better than individual plant extracts possibly due to synergism. These results suggest an important anti-microbial effect of these products on pathogens isolated from bovine mastitis with a possible applicability in this disease.

Keywords: antibiotic resistance; bovine mastitis; plant alcoholic extract; plant derived products.

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Conflict of interest statement

The authors declare no conflict of interests.

Figures

Figure 1
Figure 1
Minimum inhibitory concentrations (MIC) values (mg/mL) for 11 plant extracts.
Figure 2
Figure 2
Minimum bactericidal concentration (MBC) values (mg/mL) for 11 plant extracts.
See this image and copyright information in PMC

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