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Review
. 2017 Sep 4;17(1):132.
doi: 10.1186/s12911-017-0530-5.

Reviewing clinical guideline development tools: features and characteristics

Soudabeh Khodambashi  1 , Øystein Nytrø  2
Affiliations
Review

Reviewing clinical guideline development tools: features and characteristics

Soudabeh Khodambashi et al. BMC Med Inform Decis Mak. .

Abstract

Background: To improve consistency and streamline development and publication of clinical guidelines (GL), there is a need for appropriate software support. We have found few specific tools for the actual authoring and maintaining of GLs, and correspondingly few analyses or reviews of GL development tool functionality. In order to assist GL developers in selecting and evaluating tools, this study tries to address the perceived gap by pursuing four goals: 1) identifying available tools, 2) reviewing a representative group of tools and their supported functionalities, 3) uncovering themes of features that the studied tools support, and 4) compare the selected tools with respect to the themes.

Methods: We conducted a literature search using PubMed and Google Scholar in order to find GL development tools (GDT). We also explored tools and Content Management Systems (CMS) used in representative organisations and international communities that develop and maintain GLs. By reading a selected representative group of five GL tool manuals, exploring tools hands-on, we uncovered 8 themes of features. All found tools were compared according to these themes in order to identify the level of functionality they offer to support the GL development and publishing process. In order to limit the scope, tools for designing computer-interpretable/executable GL are excluded.

Results: After finding 1552 published papers, contacting 7 organizations and international communities, we identified a total of 19 unique tools, of which 5 tools were selected as representative in this paper. We uncovered a total of 8 themes of features according to the identified functionalities that each tool provides. Four features were common among tools: Collaborative authoring process support, user access control, GL repository management, electronic publishing. We found that the GRADE methodology was supported by three of the reviewed tools, while only two tools support annotating GL with MeSH terms. We also identified that monitoring progress, reference management, Managing versions (version control), and Change control (tracking) were often the missing features.

Conclusion: The results can promote sector discussion and eventual agreement on important tool functionality. It may aid tool and GL developers towards more efficient, and effective, GL authoring.

Keywords: Clinical guideline; Electronic guideline authoring; Guideline development process; Guideline development tool.

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Not applicable.

Competing interests

The authors declare that they have no competing interests.

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Figures

Fig. 1
Fig. 1
Selection process for literature about guideline development tools
See this image and copyright information in PMC

References

    1. Jaspers MW, Smeulers M, Vermeulen H, Peute LW. Effects of clinical decision-support systems on practitioner performance and patient outcomes: a synthesis of high-quality systematic review findings. J Am Med Inform Assoc. 2011;18(3):327–334. doi: 10.1136/amiajnl-2011-000094. - DOI - PMC - PubMed
    1. Merritt TA, Palmer D, Bergman DA, Shiono PH. Clinical practice guidelines in pediatric and newborn medicine: implications for their use in practice. Pediatrics. 1997;99(1):100–114. doi: 10.1542/peds.99.1.100. - DOI - PubMed
    1. Steinberg E, Greenfield S, Mancher M, Wolman DM, Graham R. Clinical practice guidelines we can trust.1st edition. US National Academies Press; 2011. - PubMed
    1. WHO. WHO handbook for guideline development: World Health Organization (2nd edition); 2014. http://apps.who.int/iris/bitstream/10665/145714/1/9789241548960_eng.pdf.
    1. Khodambashi S, Nytrø Ø, editors. Tool Support for Maintaining Clinical Guidelines: A Case Study. ECIME2015-9th European Conference on IS Management and Evaluation: ECIME 2015; 2015: Academic Conferences and publishing limited.

MeSH terms

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