Mechanisms of tail resorption during anuran metamorphosis

Abstract

Amphibian metamorphosis has historically attracted a good deal of scientific attention owing to its dramatic nature and easy observability. However, the genetic mechanisms of amphibian metamorphosis have not been thoroughly examined using modern techniques such as gene cloning, DNA sequencing, polymerase chain reaction or genomic editing. Here, we review the current state of knowledge regarding molecular mechanisms underlying tadpole tail resorption.

Keywords: TALEN; Xenopus; genomic editing; metamorphosis; ouro; tail resorption; targeted gene knockout.