Historical Background and Overview
- PMID: 28876854
- Bookshelf ID: NBK316258
- DOI: 10.1101/glycobiology.3e.001
Historical Background and Overview
Excerpt
This chapter provides a historical background to the field of glycobiology and an overview of this book. General terms found in the volume are considered, common monosaccharide units of glycoconjugates mentioned, and a uniform symbol nomenclature used for structural depictions presented. The major glycan classes discussed in the book are described, and an overview of the general pathways for their biosynthesis is provided. Topological issues relevant to biosynthesis and functions of glycoconjugates are also considered, and the growing role of these molecules in medicine, biotechnology, nanotechnology, bioenergy, and materials science is mentioned.
Copyright 2015-2017 by The Consortium of Glycobiology Editors, La Jolla, California. All rights reserved.
Sections
- WHAT IS GLYCOBIOLOGY?
- MONOSACCHARIDES ARE THE BASIC STRUCTURAL UNITS OF GLYCANS
- GLYCANS CAN CONSTITUTE A MAJOR PORTION OF THE MASS OF A GLYCOCONJUGATE
- MONOSACCHARIDES CAN BE LINKED TOGETHER IN MANY MORE WAYS THAN AMINO ACIDS OR NUCLEOTIDES
- COMMON MONOSACCHARIDE UNITS OF GLYCOCONJUGATES
- MAJOR CLASSES OF GLYCOCONJUGATES AND GLYCANS
- GLYCAN STRUCTURES ARE NOT ENCODED DIRECTLY IN THE GENOME
- SITE-SPECIFIC STRUCTURAL DIVERSITY IN PROTEIN GLYCOSYLATION
- CELL BIOLOGY OF GLYCOSYLATION
- TOOLS USED TO STUDY GLYCOSYLATION
- GLYCOMICS
- GLYCOSYLATION DEFECTS IN ORGANISMS AND CULTURED CELLS
- BIOLOGICAL ROLES OF GLYCANS ARE DIVERSE
- GLYCOSYLATION CHANGES IN DEVELOPMENT, DIFFERENTIATION, AND MALIGNANCY
- EVOLUTIONARY CONSIDERATIONS IN GLYCOBIOLOGY
- GLYCANS IN MEDICINE AND BIOTECHNOLOGY
- GLYCANS IN NANOTECHNOLOGY, BIOENERGY, AND MATERIALS SCIENCE
- ACKNOWLEDGMENTS
- FURTHER READING
References
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- Gagneux P, Varki A. 1999. Evolutionary considerations in relating oligosaccharide diversity to biological function. Glycobiology 9: 747–755. - PubMed
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