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Comment
. 2017 Sep 5;26(3):458-459.
doi: 10.1016/j.cmet.2017.08.020.

Disentangling High Fat, Low Carb, and Healthy Aging

Holly M Brown-Borg  1
Affiliations
Free article
Comment

Disentangling High Fat, Low Carb, and Healthy Aging

Holly M Brown-Borg. Cell Metab. .
Free article

Abstract

Dietary interventions are simple, non-invasive tools that can be utilized to improve health and lifespan. In this issue, Roberts et al. (2017) and Newman et al. (2017) reveal the physiological benefits of feeding mice ketogenic diets and suggest different underlying mechanisms that may promote healthy aging.

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Comment on

  • A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.
    Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, McMackin MZ, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA. Roberts MN, et al. Cell Metab. 2017 Sep 5;26(3):539-546.e5. doi: 10.1016/j.cmet.2017.08.005. Cell Metab. 2017. PMID: 28877457 Free PMC article.
  • Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.
    Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E. Newman JC, et al. Cell Metab. 2017 Sep 5;26(3):547-557.e8. doi: 10.1016/j.cmet.2017.08.004. Cell Metab. 2017. PMID: 28877458 Free PMC article.

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