Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Sep 6:358:j3535.
doi: 10.1136/bmj.j3535.

Fostering research into antimicrobial resistance in India

Affiliations

Fostering research into antimicrobial resistance in India

Bhabatosh Das et al. BMJ. .

Abstract

Bhabatosh Das and colleagues discuss research and development of new antimicrobials and rapid diagnostics, which are crucial for tackling antimicrobial resistance in India

PubMed Disclaimer

Conflict of interest statement

Competing interests: We have read and understood BMJ policy on declaration of interests and declare that BD, SC, and TR received support from the department of biotechnology, Government of India.

Figures

None
Fig 1 Introduction of antibiotics in clinical practice and emergence of antimicrobial resistance. The timeline shows that most new antibiotics (scaffolds) were discovered up to the 1970s. In subsequent years, these scaffolds were expanded chemically by introducing new functional groups. Few clinically used antibiotics with new scaffolds (<5) were discovered in the past 50 years. Resistance to almost all antibiotics was reported shortly after introduction in clinical practice. Relevant information was obtained from multiple sources, including https://card.mcmaster.ca/
None
Fig 2 Schematic presentation of key factors to promote antimicrobial research in India (IP=intellectual property)

References

    1. Laxminarayan R, Chaudhury RR. Antibiotic resistance in India: drivers and opportunities for action. PLoS Med 2016;13:e1001974 10.1371/journal.pmed.1001974 pmid:26934098. - DOI - PMC - PubMed
    1. Ganguly NK, Arora NK, Chandy SJ, et al. Global Antibiotic Resistance Partnership (GARP) - India Working Group. Rationalizing antibiotic use to limit antibiotic resistance in India. Indian J Med Res 2011;134:281-94.pmid:21985810. - PMC - PubMed
    1. World Health Organization (WHO). Antimicrobial resistance: Draft global action plan on antimicrobial resistance. 2015. http://www.wpro.who.int/entity/drug_resistance/resources/global_action_p... - PubMed
    1. Xiao Y, Zhang J, Zheng B, Zhao L, Li S, Li L. Changes in Chinese policies to promote the rational use of antibiotics. PLoS Med 2013;10:e1001556 10.1371/journal.pmed.1001556 pmid:24260030. - DOI - PMC - PubMed
    1. Xiao Y, Li L. The actions of China in containing antimicrobial resistance. In: Carlet J, Upham G, eds. AMR Control 2015: 46-53. http://www.globalhealthdynamics.co.uk/wp-content/uploads/2015/05/07_Xiao...

MeSH terms

Substances