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Comment
. 2017 Sep 6;37(36):8578-8580.
doi: 10.1523/JNEUROSCI.1578-17.2017.

Effects of Astroglia on Motor Neurons in Spinal Muscular Atrophy

Affiliations
Comment

Effects of Astroglia on Motor Neurons in Spinal Muscular Atrophy

Bert M Verheijen. J Neurosci. .
No abstract available

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Figures

Figure 1.
Figure 1.
Abnormal motor neuron–glia interactions in SMA. Astrocytes secrete factors to support neuron development and function. Reduced levels of secreted factors derived from cultures of murine astrocytes, specifically MCP1, induced motor neuron defects in culture. Glia and glia-secreted molecules could act as important drivers of SMA pathology. Astrocyte image based on original image from Cancer Research UK.

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