Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Aug 17;8(1):563.
doi: 10.4081/jphia.2017.563. eCollection 2017 Jun 23.

Prevalence of Squamous Cell Carcinoma of the Esophagus in a Single Tertiary Center of South Africa: A Cross Sectional Analytic Study

Mpho Kgomo  1 , Ali A Elnagar  1 , Jaco Nagel  1 , Taole Mokoena  2
Affiliations

Prevalence of Squamous Cell Carcinoma of the Esophagus in a Single Tertiary Center of South Africa: A Cross Sectional Analytic Study

Mpho Kgomo et al. J Public Health Afr. .

Abstract

The incidence of esophageal cancer varies widely in the world. In the Middle East, Africa, and Asia and parts of Europe, squamous cell carcinoma of the esophagus dominates the esophageal cancer landscape. Worldwide the rates are highest in Northern China, South Africa, Turkey and Iran. In the United States, the black population has a five-fold higher incidence of esophageal squamous cell carcinoma than the white population. To determine the prevalence of squamous cell carcinoma of the esophagus in a single tertiary center in South Africa. Patients referred to Gastroenterology Division of Steve Biko Academic Hospital for upper gastrointestinal endoscopy were recruited. Those with a known diagnoses of squamous cell carcinoma of the esophagus were recorded and those with suspicious lesions had biopsies done. These were then evaluated by an experienced histopathologist. 6118 patients were recruited. Squamous cell carcinoma was found in 59 patients giving us a prevalence of 0.96% 95%CI. The cancer was found mainly in back elderly males. The prevalence of squamous cell carcinoma of the esophagus in this single center study is 0.96%, 95% confidence interval and is a disease of black elderly males as seen elsewhere. Bigger multicenter studies are needed to further clarify this findings.

Keywords: esophagus; prevalence; squamous cell carcinoma.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Prevalence of squamous cell carcinoma: age distribution.
See this image and copyright information in PMC

References

    1. Leichman L, Thomas C. Squamous cell cancer of the esophagus: the forgotten one. Gastrointest Cancer Res 2011;4:22-3. - PMC - PubMed
    1. Day NE, Varghese C. Oosophageal cancer. Cancer Surv 1994;19-20:43-54. - PubMed
    1. Gamliel Z. Incidence, epidemiology, and etiology of esophageal cancer. Chest Surg Clin N Am 2000;10:441-50. - PubMed
    1. Wabinga HR, Parkin DM, Wabwire-Mangen, et al. Cancer in Kampala, Uganda, in 1989-91: change in incidence in the era of AIDS. Int JCancer 1993;4:26-36. - PubMed
    1. Vizcaino AP, Parkin DM, Skinner ME. Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe. Br J Cancer 1995;72:769. - PMC - PubMed

LinkOut - more resources