Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017:2017:1348749.
doi: 10.1155/2017/1348749. Epub 2017 Aug 13.

Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis

Ying Mao Gn  1 , Arvind Ponnusamy  1 , Vikram Thimma  2
Affiliations
Case Reports

Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis

Ying Mao Gn et al. Case Rep Nephrol. 2017.

Abstract

Renal complications from snakebite result in high mortality and morbidity. Acute kidney injury (AKI) occurs in 5-30% of cases. Renal manifestation could include acute tubular necrosis, cortical necrosis, interstitial nephritis, glomerulonephritis, and vasculitis. We present a case of thrombotic microangiopathy (TMA) resulting in renal cortical necrosis. Renal biopsy showed fibrin thrombi in glomeruli and arterioles with cortical necrosis. Our patient progressed to end-stage renal disease.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Arterial and arteriolar wall necrosis with luminal occlusion (thrombotic microangiopathy).
Figure 2
Figure 2
Necrotic process involving 60–70% of sampled cortex.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Isbister G. K. Snakebite doesn't cause disseminated intravascular coagulation: coagulopathy and thrombotic microangiopathy in snake envenoming. Seminars in Thrombosis and Hemostasis. 2010;36(4):444–451. doi: 10.1055/s-0030-1254053. - DOI - PubMed
    1. Casamento A. J., Isbister G. K. Thrombotic microangiopathy in two tiger snake envenomations. Anaesthesia and Intensive Care. 2011;39(6):1124–1127. - PubMed
    1. Isbister G. K., Little M., Cull G., et al. Thrombotic microangiopathy from Australian brown snake (Pseudonaja) envenoming. Internal Medicine Journal. 2007;37(8):523–528. doi: 10.1111/j.1445-5994.2007.01407.x. - DOI - PubMed
    1. Withana M., Rodrigo C., Gnanathasan A., Gooneratne L. Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: A case report. Journal of Venomous Animals and Toxins Including Tropical Diseases. 2014;20(1, article no. 26) doi: 10.1186/1678-9199-20-26. - DOI - PMC - PubMed
    1. Herath N., Wazil A., Kularatne S., et al. Thrombotic microangiopathy and acute kidney injury in hump-nosed viper (Hypnale species) envenoming: A descriptive study in Sri Lanka. Toxicon. 2012;60(1):61–65. doi: 10.1016/j.toxicon.2012.03.015. - DOI - PubMed

Publication types

LinkOut - more resources