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Comment
. 2017 Sep 8:6:e30734.
doi: 10.7554/eLife.30734.

Promiscuous bacteria have staying power

Affiliations
Comment

Promiscuous bacteria have staying power

Ruth C Massey et al. Elife. .

Abstract

Being able to take up DNA from their environment might allow pneumococcal bacteria to colonize the human nose and throat for longer periods of time.

Keywords: GWAS; S. pneumoniae; carriage duration; epidemiology; evolutionary biology; genomics; heritability; infectious disease; microbiology.

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Conflict of interest statement

No competing interests declared.

Figures

Figure 1.
Figure 1.. Streptococcus pneumoniae isolated from a child can be grown on blood agar.
Pneumococci grow as glistening colonies on agar plates. Blood is included in the agar because it provides an enzyme that can neutralize the harmful amount of hydrogen peroxide that the bacteria naturally produce.

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References

    1. Abdullahi O, Karani A, Tigoi CC, Mugo D, Kungu S, Wanjiru E, Jomo J, Musyimi R, Lipsitch M, Scott JA. Rates of acquisition and clearance of pneumococcal serotypes in the nasopharynges of children in Kilifi District, Kenya. The Journal of Infectious Diseases. 2012;206:1020–1029. doi: 10.1093/infdis/jis447. - DOI - PMC - PubMed
    1. Croucher NJ, Mostowy R, Wymant C, Turner P, Bentley SD, Fraser C. Horizontal DNA transfer mechanisms of bacteria as weapons of intragenomic conflict. PLOS Biology. 2016;14:e1002394. doi: 10.1371/journal.pbio.1002394. - DOI - PMC - PubMed
    1. Earle SG, Wu CH, Charlesworth J, Stoesser N, Gordon NC, Walker TM, Spencer CCA, Iqbal Z, Clifton DA, Hopkins KL, Woodford N, Smith EG, Ismail N, Llewelyn MJ, Peto TE, Crook DW, McVean G, Walker AS, Wilson DJ. Identifying lineage effects when controlling for population structure improves power in bacterial association studies. Nature Microbiology. 2016;1:16041. doi: 10.1038/nmicrobiol.2016.41. - DOI - PMC - PubMed
    1. Lees JA, Croucher NJ, Goldblatt D, Nosten F, Parkhill J, Turner C, Turner P, Bentley SD. Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage duration. eLife. 2017;6:e26255. doi: 10.7554/eLife.26255. - DOI - PMC - PubMed
    1. O'Brien KL, Wolfson LJ, Watt JP, Henkle E, Deloria-Knoll M, McCall N, Lee E, Mulholland K, Levine OS, Cherian T, Hib and Pneumococcal Global Burden of Disease Study Team Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. The Lancet. 2009;374:893–902. doi: 10.1016/S0140-6736(09)61204-6. - DOI - PubMed

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