Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2017 Sep;96(36):e7745.
doi: 10.1097/MD.0000000000007745.

Simultaneous endoscopic submucosal dissection for multiple early gastric cancers in a low volume center

Zhao-Sheng Chen  1 , Xi-Feng Jin, Hong-Lei Wu, Jian-Qiang Guo
Affiliations
Observational Study

Simultaneous endoscopic submucosal dissection for multiple early gastric cancers in a low volume center

Zhao-Sheng Chen et al. Medicine (Baltimore). 2017 Sep.

Abstract

The aim of the study is to evaluate the safety and efficacy of simultaneous endoscopic submucosal dissection (ESD) for multiple early gastric cancers.A total of 70 solitary early gastric cancers from 70 patients and 20 multiple early gastric cancers from 10 patients were included in this retrospective study. The curative resection rate, en bloc resection rate, procedure-related complications, and local recurrence were compared between the 2 groups.There was no statistical difference in the rate of complete resection, en bloc resection, and curative resection between the 2 groups (P > .05). No significant difference was found with respect to the occurrence of postoperative bleeding (P > .05). Procedure time was significantly longer in the simultaneous group than that in the single group (87.6 ± 25.1 min vs 54.6 ± 22.0 min, P = .004). The overall incidence of synchronous early gastric cancer was 7.5%.Simultaneous ESD for multiple early gastric cancers is a safe and feasible choice in low-volume hospital. The entire stomach should be examined meticulously during and after ESD. Larger randomized studies are needed to validate our results.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Simultaneous ESD procedure for synchronous double gastric cancer. (A) Conventional endoscopy showing the lesion of the lesser curvature of the gastric body. (B) Image of endoscopy with narrow band imaging. (C) Artificial ulcers after removal of lesion. (D) Endoscopic aspect of the lesion after ESD. (E) Conventional endoscopy showing the lesion of the antrum. (F) Image of endoscopy with narrow band imaging. (G) Artificial ulcers after the removal of lesion. (H) Endoscopic aspect of the lesion after ESD. ESD = endoscopic submucosal dissection.
See this image and copyright information in PMC

References

    1. Morita M, Kuwano H, Baba H, et al. Multifocal occurrence of gastric carcinoma in patients with a family history of gastric carcinoma. Cancer 1998;83:1307–11. - PubMed
    1. Ribeiro U, Jorge UM, Safatle-Ribeiro AV, et al. Clinicopathologic and immunohistochemistry characterization of synchronous multiple primary gastric adenocarcinoma. J Gastrointest Surg 2007;11:233–9. - PubMed
    1. Otsuji E, Kuriu Y, Ichikawa D, et al. Clinicopathologic characteristics and prognosis of synchronous multifocal gastric carcinomas. Am J Surg 2005;189:116–9. - PubMed
    1. Gotoda T, Yanagisawa A, Sasako M, et al. Incidence of lymph node metastasis from early gastric cancer: estimation with a large number of cases at two large centers. Gastric Cancer 2000;3:219–25. - PubMed
    1. Isomoto H, Shikuwa S, Yamaguchi N, et al. Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study. Gut 2009;58:331–6. - PubMed

Publication types