Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Sep 8;9(9):996.
doi: 10.3390/nu9090996.

Weight Management Interventions in Women with and without PCOS: A Systematic Review

Affiliations

Weight Management Interventions in Women with and without PCOS: A Systematic Review

Josefin Kataoka et al. Nutrients. .

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrinopathy among women associated with reproductive, metabolic and psychological features. While weight management is recommended as first-line treatment, it is unclear if women with PCOS achieve similar benefits as women without PCOS. This systematic review thus aimed to compare the efficacy of weight management interventions in women with and without PCOS. Databases were searched until May 2017. The primary outcome was weight and anthropometric, reproductive, metabolic and psychological measures were secondary outcomes. Of 3264 articles identified, 14 studies involving n = 933 (n = 9 high and n = 5 moderate risk of bias) met the inclusion criteria. No statistically significant differences in weight or weight loss following the intervention were found between women with and without PCOS in five studies, with the remaining studies not comparing the difference in weight or weight loss between these groups. Secondary outcomes did not differ significantly between the two groups. This review identified that there is a paucity of high quality research in this area and that more rigorous research is needed.

Keywords: insulin resistance; obesity; polycystic ovary syndrome; systematic review; weight loss.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest. None of the funders had any role in the design, analysis or writing of this article.

Figures

Figure 1
Figure 1
Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram.

References

    1. March W.A., Moore V.M., Willson K.J., Phillips D.I., Norman R.J., Davies M.J. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum. Reprod. 2010;25:544–551. doi: 10.1093/humrep/dep399. - DOI - PubMed
    1. Asuncion M., Calvo R.M., San Millan J.L., Sancho J., Avila S., Escobar-Morreale H.F. A prospective study of the prevalence of the polycystic ovary syndrome in unselected caucasian women from Spain. J. Clin. Endocrinol. Metab. 2000;85:2434–2438. doi: 10.1210/jc.85.7.2434. - DOI - PubMed
    1. Diamanti-Kandarakis E., Kouli C.R., Bergiele A.T., Filandra F.A., Tsianateli T.C., Spina G.G., Zapanti E.D., Bartzis M.I. A survey of the polycystic ovary syndrome in the Greek island of Lesbos: Hormonal and metabolic profile. J. Clin. Endocrinol. Metab. 1999;84:4006–4011. doi: 10.1210/jcem.84.11.6148. - DOI - PubMed
    1. Stepto N.K., Cassar S., Joham A.E., Hutchison S.K., Harrison C.L., Goldstein R.F., Teede H.J. Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp. Hum. Reprod. 2013;28:777–784. doi: 10.1093/humrep/des463. - DOI - PubMed
    1. Moran L.J., Misso M.L., Wild R.A., Norman R.J. Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: A systematic review and meta-analysis. Hum. Reprod. Update. 2010;16:347–363. doi: 10.1093/humupd/dmq001. - DOI - PubMed

Publication types

LinkOut - more resources