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Comment
. 2017 Sep 7;170(6):1055-1056.
doi: 10.1016/j.cell.2017.08.031.

Converting Cold into Hot Tumors by Combining Immunotherapies

John B A G Haanen  1
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Free article
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Converting Cold into Hot Tumors by Combining Immunotherapies

John B A G Haanen. Cell. .
Free article

Abstract

In a small phase Ib study in this issue of Cell, Ribas et al. report that the combination of intralesional injection of a modified human herpes simplex virus and systemic anti-PD-1 treatment resulted in a 62% response rate in patients with metastatic melanoma, accompanied by enhanced T cell infiltration in virus-injected lesions.

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