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. 2018 Feb:43:128-132.
doi: 10.1016/j.jcrc.2017.08.035. Epub 2017 Aug 24.

Tranexamic acid for refractory gastrointestinal bleeds: A cohort study

Joanna L Stollings  1 , Janna S Landsperger  2 , Matthew W Semler  3 , Todd W Rice  2
Affiliations

Tranexamic acid for refractory gastrointestinal bleeds: A cohort study

Joanna L Stollings et al. J Crit Care. 2018 Feb.
No abstract available

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Conflict of interest statement

Financial Support: None

Conflicts of Interest: Joanna L. Stollings, Janna S. Landsperger, and Matthew W. Semler have no conflicts of interest to disclose;

Figures

Figure 1
Figure 1
Flow diagram of patients that received tranexamic acid for gastrointestinal bleeds in the Medical Intensive Care Unit Definition of abbreviations: DIC=disseminated intravascular coagulopathy; GI=gastrointestinal; LUE=left upper extremity; MICU=medical intensive care unit
Figure 2
Figure 2
Number of blood products transferred before and after tranexamic acid administration
See this image and copyright information in PMC

References

    1. Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med. 2013;368(1):11–21. - PubMed
    1. Cook DJ, Griffith LE, Walter SD, et al. The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients. Crit Care. 2001;5(6):368–375. - PMC - PubMed
    1. Cook DJ, Fuller HD, Guyatt GH, et al. Risk factors for gastrointestinal bleeding in critically ill patients. Canadian Critical Care Trials Group. N Engl J Med. 1994;330(6):377–381. - PubMed
    1. collaborators C-t. Shakur H, Roberts I, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet. 2010;376(9734):23–32. - PubMed
    1. Gluud LL, Klingenberg SL, Langholz SE. Systematic review: tranexamic acid for upper gastrointestinal bleeding. Aliment Pharmacol Ther. 2008;27(9):752–758. - PubMed