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. 2017 Sep 26;15(37):7894-7897.
doi: 10.1039/c7ob02013a.

A new synthetic method for non-symmetric pillar[5]arenes with simple isolation and improved yield

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A new synthetic method for non-symmetric pillar[5]arenes with simple isolation and improved yield

Jiaming Ding et al. Org Biomol Chem. .

Abstract

The conventional method to synthesize non-symmetric pillar[n]arenes (PA[n]s) generally results in a low yield and requires laborious isolation. We developed a new synthetic method to prepare non-symmetric PA[5]s with various substitutions. Monomers were synthesized starting from commercially available chemicals. The desired products could be easily isolated with an improved yield.

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