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Review
. 2017 Sep;36(3):124-130.
doi: 10.12788/j.sder.2017.0137.

Atopic dermatitis: emerging therapies

Eric Simpson  1 , Jeremy Udkoff  2   3 , Jenna Borok  2   3 , Wynnis Tom  2   3 , Lisa Beck  4 , Lawrence F Eichenfield  2   3
Affiliations
Review

Atopic dermatitis: emerging therapies

Eric Simpson et al. Semin Cutan Med Surg. 2017 Sep.

Abstract

Crisaborole and dupilumab represent the first 2 Food and Drug Administration (FDA)-approved therapies for atopic dermatitis (AD) in more than 15 years, and there are many promising drugs currently in development. This new wave of therapeutics capitalizes on the large body of work clarifying the pathogenesis of AD over the last several decades. In particular, type 2 cytokine-driven inflammation and skin barrier dysfunction are key processes underlying AD pathogenesis.

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