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. 2017 Sep;112(9):632-639.
doi: 10.1590/0074-02760160553.

Exposure source prevalence is associated with gender in hepatitis C virus patients from Rio de Janeiro, Brazil

Daniele Blasquez Olmedo  1 , Patrícia Marraccini Precioso  1 , António Lugdero-Correia  1 , Guida da Silva  2 , Angela Maria Guimarães Dos Santos  1 , Luís Cristóvão Pôrto  1
Affiliations

Exposure source prevalence is associated with gender in hepatitis C virus patients from Rio de Janeiro, Brazil

Daniele Blasquez Olmedo et al. Mem Inst Oswaldo Cruz. 2017 Sep.

Abstract

Background: Hepatitis C virus (HCV) infection is a worldwide public health problem. A characterisation of the differences in exposure sources among genders will enable improvements in surveillance actions.

Methods: Exposure data were obtained for 1180 confirmed HCV cases Brazil's mandatory reporting to epidemiological surveillance, which was directed by a reference laboratory in Rio de Janeiro, Brazil. The Chi-square test (χ2) was used to assess the associations between exposure sources and gender. The prevalence ratio (PR) was calculated for exposures that showed an association.

Results: The results showed 57.7% cases were female, and associations with snorting drugs, sexual activity, surgery, aesthetic procedures, blood transfusions, and educational level were observed (p < 0.001). Men showed 2.53 (1.33-3.57), 4.83 (3.54-6.59), and 2.18 (1.33-3.57) times more exposure to sniffing drugs, risky sex and higher levels of education, respectively, than women. Women demonstrated 4.46 (3.21-6.21), 1.94 (1.43-2.63), and 3.10 (2.09-4.61) times more exposure to surgery, aesthetic procedures, and blood transfusions, respectively, than men.

Conclusion: Our results showed differences in risk behaviours associated with gender among HCV carriers. These data are likely to significantly influence clinical practice regarding the adoption of specific approaches for counselling and control policies to prevent the emergence of new cases and break the chain of transmission of the virus.

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References

    1. Cavalheiro NP. Sexual transmission of hepatitis C. Rev Inst Med Trop Sao Paulo. 2007;49(5):271–277. - PubMed
    1. CDC - Centers for Disease Control and Prevention Recommendations for the identification of chronic hepatitis C virus infection among persons born during 1945-1965. 2012 http://www.cdc.gov/mmwr/preview/mmwrhtml/rr6104a1.htm - PubMed
    1. Cullen KJ, Hope VD, Croxford S, Shute J, Ncube F, Parry JV. Factors associated with recently acquired hepatitis C virus infection in people who inject drugs in England, Wales and Northern Ireland: new findings from an unlinked anonymous monitoring survey. Epidemiol Infect. 2015;143(7):1398–1407. - PMC - PubMed
    1. El-Ghitany EM, Wahab MMA, El-Wahab EWA, Hassouna S, Farghaly AG. A comprehensive hepatitis C virus risk factors meta-analysis (1989-2013): do they differ in Egypt? Liver Int. 2015;35(2):489–501. - PubMed
    1. Fernández-Dávila P, Folch C, Ferrer L, Soriano R, Diez M, Casabona J. Hepatitis C virus infection and its relationship to certain sexual practices in men-who-have-sex-with-men in Spain: results from the European MSM Internet Survey (EMIS) Enferm Infecc Microbiol Clin. 2015;33(5):303–310. - PubMed