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Review
. 2017 May 8:27:14.
doi: 10.11604/pamj.2017.27.14.8977. eCollection 2017.

[Primary cerebral gliosarcoma: about two cases and review of the literature]

[Article in French]
Mohamed Amine Azami  1 , Iliass El Alami  2 , Imane Bourhafour  3 , Salwa Belhabib  1 , Mohamed Oukabli  1 , Abderrahmane Albouzidi  1
Affiliations
Review

[Primary cerebral gliosarcoma: about two cases and review of the literature]

[Article in French]
Mohamed Amine Azami et al. Pan Afr Med J. .

Abstract
in English, French

Gliosarcoma is a very rare brain tumor accounting for 1.8 -8% of all glial tumors. It has been classified by the World Health Organization as a variant of glioblastoma. It is a tumor with double glial and sarcomatous component. Patient's clinical picture is polymorphic, imaging data are evocative, diagnosis is based on histology. Treatment is always surgical. Prognosis is closely linked to the quality of resection. We here report two clinical cases with the aim of assessing the diagnostic, therapeutic and prognostic features of this rare entity.

Le gliosarcome est une tumeur cérébrale très rare représentant 1,8 à 8% de l’ensemble des tumeurs gliales. Il est considéré par l’organisation mondiale de la santé comme une variante de glioblastome. C’est une tumeur à double composante gliale et sarcomateuse. Le tableau clinique est polymorphe, les données de l’imagerie sont évocatrices, la confirmation est histologique. Le traitement est essentiellement chirurgical. Le pronostic est lié étroitement à la qualité d’exérèse. Dans notre travail Nous rapportons deux observations cliniques dont l’objectif est de faire le point sur les particularités, essentiellement diagnostiques, thérapeutiques ainsi que pronostiques de cette entité rare.

Keywords: Primary gliosarcome; central nervous system; diagnosis; treatment.

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Figures

Figure 1
Figure 1
IRM cérébrale, séquence T1 avec injection de gadolinium: volumineux processus tumoral gauche entrant en contact avec la dure mère associé à un œdème péri-lésionnel et un effet de masse
Figure 2
Figure 2
Prolifération tumorale faite de deux composantes gliale (à droite) et sarcomateuse (à gauche), HEx100
See this image and copyright information in PMC

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