Cervical Lymph Nodes: Harbinger of Benign Inclusions As Well As Metastatic Deposits of Thyroid Malignancy
- PMID: 28904927
- PMCID: PMC5590390
- DOI: 10.4103/ijabmr.IJABMR_36_16
Cervical Lymph Nodes: Harbinger of Benign Inclusions As Well As Metastatic Deposits of Thyroid Malignancy
Abstract
Lymph nodes can be harbinger to benign epithelial inclusions as well as metastatic deposits. Cervical lymph nodes are home to benign epithelial inclusions from thyroid better known as lateral aberrant thyroid as well as inclusions from salivary gland due to the unique embryologic origins of nodes with these organs. We present a case of a young female suspected of thyroid malignancy who was intraoperative diagnosed by frozen sections with papillary carcinoma of the thyroid along with bilateral cervical nodes (Level I-V) positive for reactive lymphadenopathy with Level II node being positive to benign salivary gland inclusions and Level VI node being positive to metastatic deposits of papillary carcinoma of the thyroid.
Keywords: Aberrant thyroid inclusions; benign epithelial inclusions; cervical lymph nodes; metastatic deposits.
Conflict of interest statement
There are no conflicts of interest.
Figures


Similar articles
-
Histopathologic and immunohistochemical characterization of a primary papillary thyroid carcinoma in the lateral cervical lymph node.Exp Mol Pathol. 2007 Feb;82(1):91-4. doi: 10.1016/j.yexmp.2006.09.003. Epub 2006 Nov 22. Exp Mol Pathol. 2007. PMID: 17123508
-
Benign Intranodal Thyroid Tissue Similar to Nodal Metastasis of Thyroid Papillary Carcinoma: A Rare Case Report.Diagnostics (Basel). 2023 Feb 3;13(3):577. doi: 10.3390/diagnostics13030577. Diagnostics (Basel). 2023. PMID: 36766682 Free PMC article.
-
[Role of level VI lymph nodes metastasis in cervical metastasis of patients with papillary thyroid cancer].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010 Aug;45(8):664-8. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010. PMID: 21055244 Chinese.
-
[The lymph node dissection in thyroid carcinoma].Ann Ital Chir. 2006 May-Jun;77(3):187-97. Ann Ital Chir. 2006. PMID: 17137033 Review. Italian.
-
Thyroid carcinomas found incidentally in the cervical lymph nodes: do they arise from heterotopic thyroid tissues?J Oral Maxillofac Surg. 2008 Dec;66(12):2566-76. doi: 10.1016/j.joms.2008.06.025. J Oral Maxillofac Surg. 2008. PMID: 19022137 Review.
Cited by
-
Clinicopathological features of incidentally detected metastatic thyroid papillary carcinoma in cervical lymph nodes of non-thyroid cancer patients: a retrospective analysis of 31cases.Diagn Pathol. 2023 Jul 15;18(1):82. doi: 10.1186/s13000-023-01370-4. Diagn Pathol. 2023. PMID: 37454141 Free PMC article.
References
-
- Longo S. Benign lymph node inclusions. Hum Pathol. 1976;7:349–54. - PubMed
-
- Brooks JS, LiVolsi VA, Pietra GG. Mesothelial cell inclusions in mediastinal lymph nodes mimicking metastatic carcinoma. Am J Clin Pathol. 1990;93:741–8. - PubMed
-
- Carcangiu ML, Zampi G, Pupi A, Castagnoli A, Rosai J. Papillary carcinoma of the thyroid. A clinicopathologic study of 241 cases treated at the University of Florence, Italy. Cancer. 1985;55:805–28. - PubMed
-
- Kheir SM, Mann WJ, Wilkerson JA. Glandular inclusions in lymph nodes. The problem of extensive involvement and relationship to salpingitis. Am J Surg Pathol. 1981;5:353–9. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials