Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Dec;20(4):354-358.
doi: 10.1007/s10047-017-0992-3. Epub 2017 Sep 13.

Extracorporeal membrane oxygenation in spina bifida and (H1N1)-induced acute respiratory distress syndrome

Oliver Jansen  1 , Oliver Kamp  2 , Christian Waydhas  2   3 , Valentin Rausch  2 , Thomas Armin Schildhauer  2 , Justus Strauch  4 , Dirk Buchwald  4 , Uwe Hamsen  2
Affiliations
Case Reports

Extracorporeal membrane oxygenation in spina bifida and (H1N1)-induced acute respiratory distress syndrome

Oliver Jansen et al. J Artif Organs. 2017 Dec.

Abstract

Acute respiratory distress syndrome (ARDS) is characterized as an acute hypoxemic and/or hypercapnic respiratory failure seen in critically ill patients and is still, although decreased over the past few years, associated with high mortality. Furthermore, ARDS may be a life-threatening complication of H1N1 pneumonia. We report on a 45-year-old spina bifida patient with confirmed H1N1 influenza virus infection causing acute respiratory failure, who was successfully weaned from 42-day veno-venous extracorporeal membrane oxygenation (vv-ECMO) treatment with an excellent outcome. Due to the physical constitution of spina bifida patients, we experienced challenges concerning cannula positioning and mechanical ventilation settings during weaning.

Keywords: Acute respiratory distress syndrome; Extracorporeal membrane oxygenation; H1N1; Spina bifida; Spinal cord injury.

PubMed Disclaimer

Conflict of interest statement

All the authors of this article report that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Chest and abdomen X-ray overview in anteroposterior view. Significantly deforming scoliosis
Fig. 2
Fig. 2
Chest X-ray in anteroposterior view and CT scan in supine position at the time of admission. Bilateral opacities, posterior consolidation of lung fields
Fig. 3
Fig. 3
CT scan in supine (left) and prone position (right). Alveolar recruitment of dorsal lung fields in prone position, starting consolidation of anterior lung fields
See this image and copyright information in PMC

References

    1. ARDS Definition Task Force. Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012;307:2526–2533. - PubMed
    1. Combes A, Brodie D, Bartlett R, Brochard L, Brower R, Conrad S, De Backer D, Fan E, Ferguson N, Fortenberry J, Fraser J, Gattinoni L, Lynch W, MacLaren G, Mercat A, Mueller T, Ogino M, Peek G, Pellegrino V, Pesenti A, Ranieri M, Slutsky A, Vuylsteke A, International ECMO network (ECMONet) Position paper for the organization of extracorporeal membrane oxygenation programs for acute respiratory failure in adult patients. Am J Respir Crit Care Med. 2014;190:488–496. doi: 10.1164/rccm.201404-0630CP. - DOI - PubMed
    1. Australia and New Zealand Extracorporeal Membrane Oxygenation (ANZ ECMO. ) Influenza Investigators. Davies A, Jones D, Bailey M, Beca J, Bellomo R, Blackwell N, Forrest P, Gattas D, Granger E, Herkes R, Jackson A, McGuinness S, Nair P, Pellegrino V, Pettilä V, Plunkett B, Pye R, Torzillo P, Webb S, Wilson M, Ziegenfuss M. Extracorporeal membrane oxygenation for influenza A (H1N1) acute respiratory distress syndrome. JAMA. 2009;302:1888–1895. doi: 10.1001/jama.2009.1535. - DOI - PubMed
    1. Peek GJ, Mugford M, Tiruvoipati R, Wilson A, Allen E, Thalanany MM, Hibbert CL, Truesdale A, Clemens F, Cooper N, Firmin RK, Elbourne D. CESAR trial collaboration. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomized controlled trial. The Lancet. 2009;374:1351–1363. doi: 10.1016/S0140-6736(09)61069-2. - DOI - PubMed
    1. Cochi SE, Kempker JA, Annangi S, Kramer MR, Martin GS. Mortality trends of acute respiratory distress syndrome in the United States from 1999 to 2013. Ann Am Thorac Soc. 2016;13:1742–1751. - PMC - PubMed

Publication types

MeSH terms