Early vulvar and umbilical incisional scar recurrence of cervical squamous cell carcinoma: Earlier than usually expected

Abstract

Cutaneous metastasis is considered as a hazardous condition depending on the mean survival around 9 months, which usually originates from cancers of the breast, lung, ovary, colon, and rarely from the cervix. The crucial prognostic factor of cutaneous metastasis depends on the period between the primary malignancy and cutaneous metastasis. We report two cases of the unusual presentation of squamous cell cancer of the cervix that developed vulvar and umbilical metastasis in the 5^th month of primary treatment. Both of our patients survived for 11 months following the primary treatment. In addition, our first case is the earliest vulvar recurrence of cervical carcinoma in the English literature following appropriate medical and surgical management.

Keywords: Squamous cell cervical cancer; umbilical metastasis; vulvar metastasis.

Figure 1. A 2x3-cm ulcerated fragile, firm, nodular lesion with irregular boundaries on the right labium majus with focal central hemorrhage

Figure 2. Infiltrating tumor nests consisting of atypical squamous cells with large abundant eosinophilic cytoplasm and a large vesicular nucleus with prominent nucleoli

Figure 3. Computerized tomography image of metastatic umbilical mass