Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Mar;17(1):25-27.
doi: 10.7181/acfs.2016.17.1.25. Epub 2016 Mar 21.

Cutaneous Horn in Premalignant and Malignant Conditions

Affiliations

Cutaneous Horn in Premalignant and Malignant Conditions

Hyochun Park et al. Arch Craniofac Surg. 2016 Mar.

Abstract

Cutaneous horns are conical, circumscribed protuberances formed by densely layered keratin. These lesions originate from basal keratinocytes and may manifest as benign, premalignant, or malignant cutaneous pathology in chronically sun-damaged areas. Complete surgical excision with histologic examination is needed for potential malignancy. In this report, we describe two elderly women presenting with solitary facial cutaneous horns, which were respectively diagnosed as actinic keratosis and squamous cell carcinoma.

Keywords: Carcinoma, squamous cell; Cutaneous horn; Keratosis, actinic.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1. Case 1. (A) A 1.5 cm tall firm arciform projection with broad base. (B) Postoperative appearance after wide excision and advancement flap.
Fig. 2
Fig. 2. Case 1. Histology of the lesion demonstrates thick cornified mound atop stratum Malpighii (H&E, ×20).
Fig. 3
Fig. 3. Case 2. (A) A 1.8 cm cutaneous horn of right preauricular area. (B) Postoperative appearance at 2 months after surgery.
Fig. 4
Fig. 4. Case 2. Histologic section consistent with well-differentiated squamous cell carcinoma. Note dermal infiltrates of primary cutaneous cellular sheets and nests, with intensely inflamed advancing edge (H&E, ×20).

References

    1. Yu RC, Pryce DW, Macfarlane AW, Stewart TW. A histopathological study of 643 cutaneous horns. Br J Dermatol. 1991;124:449–452. - PubMed
    1. Kim YJ, Oh ST, Kang H, Park CJ, Park YM, Cho SH, et al. Clinicopathologic study of cutaneous horns. Korean J Dermatol. 2005;43:359–365.
    1. Copcu E, Sivrioglu N, Culhaci N. Cutaneous horns: are these lesions as innocent as they seem to be? World J Surg Oncol. 2004;2:18. - PMC - PubMed
    1. Pyne J, Sapkota D, Wong JC. Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base. Dermatol Pract Concept. 2013;3:3–7. - PMC - PubMed
    1. Mantese SA, Diogo PM, Rocha A, Berbert AL, Ferreira AK, Ferreira TC. Cutaneous horn: a retrospective histopathological study of 222 cases. An Bras Dermatol. 2010;85:157–163. - PubMed

LinkOut - more resources