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. 2017 Aug 10;6(3):60.
doi: 10.21699/jns.v6i3.535. eCollection 2017 Jul-Sep.

Neonatal Perforated Appendicitis Attributed to Localized Necrotizing Enterocolitis of the Appendix: A Review

Andrew Tumen  1 , Pranit N Chotai  1   2 , John Matthew Williams  3 , Adrianne Myers-Webb  1 , Ramesh Krishnan  3 , James W Eubanks Iii  1
Affiliations

Neonatal Perforated Appendicitis Attributed to Localized Necrotizing Enterocolitis of the Appendix: A Review

Andrew Tumen et al. J Neonatal Surg. .

Abstract

Neonatal appendicitis is a rare clinical entity associated with remarkable morbidity and mortality. Appendicular perforation is common and the diagnosis is usually made intra-operatively. The causative etiology of neonatal perforated appendicitis (NPA) is a subject of debate and has not been elucidated. Although many etiologic theories exist, increasing evidence suggests a subset of NPA cases may represent a form of necrotizing enterocolitis (NEC) localized to the appendix. We herein present a review of the current literature to include cases of NPA attributed to localized NEC. A high index of clinical suspicion and early laparotomy are recommended.

Keywords: Neonatal perforated appendicitis; localized NEC.; necrotizing enterocolitis; neonatal appendicitis.

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Figures

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Figure 1: Patient characteristics from literature review
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Table 1: Reported cases of neonatal perforated appendicitis with necrotizing enterocolitis as an underlying etiology
See this image and copyright information in PMC

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