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Clinical Trial
. 1987 Nov;22(9):1038-40.
doi: 10.3109/00365528708991953.

Olsalazine in patients intolerant of sulphasalazine

Affiliations
Clinical Trial

Olsalazine in patients intolerant of sulphasalazine

A Ireland et al. Scand J Gastroenterol. 1987 Nov.

Abstract

Fifty patients with ulcerative colitis, intolerant of sulphasalazine, were treated with 500 mg olsalazine twice daily for a 3-month trial period. Thirty-eight of the patients (76%) tolerated the drug well, and all continued to take it beyond the 3-month period. Twelve (24%) were withdrawn because of side effects, the commonest being diarrhoea. There were no haematologic or biochemical abnormalities. Thus, olsalazine is a useful drug for patients who are intolerant of sulphasalazine.

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