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Comment
. 2017 Sep 19:6:e31082.
doi: 10.7554/eLife.31082.

Flipping the switch

Xavier Pierrat  1 , Alexandre Persat  1
Affiliations
Comment

Flipping the switch

Xavier Pierrat et al. Elife. .

Abstract

A structural switch controls the architecture of Vibrio cholerae biofilms by mediating the interactions between two matrix components.

Keywords: RbmA; VPS; Vibrio cholerae; biofilm; biophysics; infectious disease; matrix protein; microbiology; protease; structural biology.

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Conflict of interest statement

No competing interests declared.

Figures

Figure 1.
Figure 1.. Inside a biofilm.
(A) Vibrio cholerae (white) secretes four main matrix proteins: RbmA (blue), RbmC (orange), Bap1 (green) and VPS (red strands). (B) An RbmA monomer (blue and black) binds to VPS (red). (C) An RbmA dimer can bind to several strands of VPS to create a stable mesh across the matrix.
See this image and copyright information in PMC

Comment on

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