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. 2017 Oct;23(10):1627-1630.
doi: 10.3201/eid2310.170845.

Surveillance of Extrapulmonary Nontuberculous Mycobacteria Infections, Oregon, USA, 2007-2012

Emily Henkle, Katrina Hedberg, Sean D Schafer, Kevin L Winthrop

Surveillance of Extrapulmonary Nontuberculous Mycobacteria Infections, Oregon, USA, 2007-2012

Emily Henkle et al. Emerg Infect Dis. 2017 Oct.

Abstract

Limited data are available describing extrapulmonary nontuberculous mycobacteria (NTM) infections in the general population. We describe results from statewide population-based laboratory surveillance in Oregon, USA, during 2007-2012. We defined a case of extrapulmonary NTM infection as >1 isolate from skin/soft tissue, disseminated sites, lymph node, joint, or other sites. The annual incidence of extrapulmonary NTM infection (other than Mycobacterium gordonae) was stable, averaging 1.5 cases/100,000 population. Median age of the 334 patients was 51 years, and 53% of patients were female. Half of cases were caused by M. avium complex, but rapid-growing NTM species accounted for one third of cases. Most extrapulmonary NTM infections are skin/soft tissue. Compared with pulmonary NTM infection, more extrapulmonary infections are caused by rapid-growing NTM species. the designation of NTM as a reportable disease in Oregon in 2014 will result in better detection of changes in the incidence and patterns of disease in the future.

Keywords: Mycobacterium avium complex; Oregon; Public health surveillance; bacteria; extrapulmonary nontuberculous mycobacteria; incidence; nontuberculous mycobacteria; tuberculosis and other mycobacteria.

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Figures

Figure
Figure
Observed incidence (cases/100,000 population) of extrapulmonary nontuberculous mycobacterium infection (excluding Mycobacterium gordonae), Oregon, USA, 2007–2012.
See this image and copyright information in PMC

References

    1. Lyman MM, Grigg C, Kinsey CB, Keckler MS, Moulton-Meissner H, Cooper E, et al. Invasive nontuberculous mycobacterial infections among cardiothoracic surgical patients exposed to heater-cooler devices. Emerg Infect Dis. 2017;23:796–805. 10.3201/eid2305.161899 - DOI - PMC - PubMed
    1. Schnabel D, Esposito DH, Gaines J, Ridpath A, Barry MA, Feldman KA, et al.; RGM Outbreak Investigation Team. Multistate US outbreak of rapidly growing mycobacterial infections associated with medical tourism to the Dominican Republic, 2013–2014. Emerg Infect Dis. 2016;22:1340–7. 10.3201/eid2208.151938 - DOI - PMC - PubMed
    1. Winthrop KL, Abrams M, Yakrus M, Schwartz I, Ely J, Gillies D, et al. An outbreak of mycobacterial furunculosis associated with footbaths at a nail salon. N Engl J Med. 2002;346:1366–71. 10.1056/NEJMoa012643 - DOI - PubMed
    1. Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, et al.; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175:367–416. 10.1164/rccm.200604-571ST - DOI - PubMed
    1. Henkle E, Hedberg K, Schafer S, Novosad S, Winthrop KL. Population-based incidence of pulmonary nontuberculous mycobacterial disease in Oregon 2007 to 2012. Ann Am Thorac Soc. 2015;12:642–7. 10.1513/AnnalsATS.201412-559OC - DOI - PMC - PubMed

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