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. 2017 Oct 3;53(79):10922-10925.
doi: 10.1039/c7cc03387g.

Lipid radicals cause light-induced retinal degeneration

Masataka Enoki  1 , Saki Shinto, Yuta Matsuoka, Ayasa Otsuka, Sachiko Kaidzu, Masaki Tanito, Takahiro Shibata, Koji Uchida, Akihiro Ohira, Mayumi Yamato, Ken-Ichi Yamada
Affiliations

Lipid radicals cause light-induced retinal degeneration

Masataka Enoki et al. Chem Commun (Camb). .

Abstract

Age-related macular degeneration (AMD) is the leading cause of blindness worldwide. Although the cause of AMD remains unknown, lipid peroxidation (LPO) end-products are critical molecules for its development. Herein, we report the imaging of lipid radicals, which are key factors in the LPO reaction, and therapeutic information using animal models.

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