The global impact of IBS: time to think about IBS-specific models of care?
- PMID: 28932273
- PMCID: PMC5598808
- DOI: 10.1177/1756283X17718677
The global impact of IBS: time to think about IBS-specific models of care?
Abstract
Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal (GI) disorder that can significantly erode the quality of life (QoL) of sufferers and places a major cost burden on healthcare services. This paper reviews the literature on the impact of IBS on healthcare services and society, including a recent report on the subject, in order to formulate a plan for the future. A completely different model of care for these patients is recommended based on this review and the experience of the two authors who have been treating patients with functional GI disorders for 20 and 35 years, respectively.
Keywords: IBS; burden; model of care.
Conflict of interest statement
Conflict of interest statement: The authors declare the following conflicts of interest. Maura Corsetti is a speaker for Shire and Menarini and is a consultant for Allergan. Peter Whorwell has acted as a consultant for, or received research grant support from, the following pharmaceutical companies in the last 5 years: Almirall Pharma, Boehringer–Ingelheim, Chr. Hansen, Danone Research, Ironwood Pharmaceuticals, Salix, Shire UK, Sucampo Pharmaceuticals and Allergan.
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References
-
- Cremonini F, Talley NJ. Irritable bowel syndrome: epidemiology, natural history, health care seeking and emerging risk factors. Gastroenterol Clin North Am 2005; 34: 189–204. - PubMed
-
- Gwee KA. Irritable bowel syndrome in developing countries: a disorder of civilization or colonization? Neurogastroenterol Motil 2005; 17: 317–324. - PubMed
-
- World Gastroenterology Organisation Global Guidelines. Irritable bowel syndrome: a global perspective. Updated September 2015, www.worldgastroenterology.org/guidelines/global-guidelines/irritable-bow.... - PubMed
-
- Camilleri M, Lasch K, Zhou W. Irritable bowel syndrome: methods, mechanisms, and pathophysiology. The confluence of increased permeability, inflammation, and pain in irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol 2012; 303: G775– G785. - PubMed
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