The J-ALEX trial-is frontline alectinib a new standard of care?
- PMID: 28932515
- PMCID: PMC5594119
- DOI: 10.21037/jtd.2017.06.134
The J-ALEX trial-is frontline alectinib a new standard of care?
Conflict of interest statement
Conflicts of Interest: The authors have no conflicts of interest to declare.
Comment on
-
Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial.Lancet. 2017 Jul 1;390(10089):29-39. doi: 10.1016/S0140-6736(17)30565-2. Epub 2017 May 10. Lancet. 2017. PMID: 28501140 Clinical Trial.
Similar articles
-
Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial.Lancet. 2017 Jul 1;390(10089):29-39. doi: 10.1016/S0140-6736(17)30565-2. Epub 2017 May 10. Lancet. 2017. PMID: 28501140 Clinical Trial.
-
J-ALEX trial will crown alectinib as the standard choice for anaplastic lymphoma kinase positive untreated non-small cell lung cancer patients?J Thorac Dis. 2018 Jan;10(1):106-108. doi: 10.21037/jtd.2017.12.76. J Thorac Dis. 2018. PMID: 29600033 Free PMC article. No abstract available.
-
Patient-reported outcomes from the randomized phase III ALEX study of alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer.Lung Cancer. 2019 Dec;138:79-87. doi: 10.1016/j.lungcan.2019.10.002. Epub 2019 Oct 11. Lung Cancer. 2019. PMID: 31654838 Clinical Trial.
-
Alectinib for treatment of ALK-positive non-small-cell lung cancer.Future Oncol. 2017 Feb;13(4):321-335. doi: 10.2217/fon-2016-0386. Epub 2016 Oct 26. Future Oncol. 2017. PMID: 27780368 Review.
-
Alectinib for ALK-positive non-small-cell lung cancer.Expert Rev Clin Pharmacol. 2016 Aug;9(8):1005-13. doi: 10.1080/17512433.2016.1195262. Epub 2016 Jun 21. Expert Rev Clin Pharmacol. 2016. PMID: 27232673 Review.
References
-
- 1. National Comprehensive Cancer Network. Non-Small Cell Lung Cancer (Version 5. 2017). Available online: https://www.nccn.org/professionals/physician_gls/pdf/nscl.pdf
-
- Felip E, Bauer T, Solomon B, et al. Safety and efficacy of lorlatinib (PF-06463922) in patients with advanced ALK+ or ROS1+ non-small-cell lung cancer (NSCLC). J Thorac Oncol 2017;12:S383-4. 10.1016/j.jtho.2016.11.433 - DOI
-
- Reckamp KL, Wakelee HA, Patel S, et al. CNS activity of ensartinib in ALK+ non-small cell lung cancer (NSCLC) patients (pts). J Thorac Oncol 2017;28: ii28-ii51.
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources