The J-ALEX trial-is frontline alectinib a new standard of care?
- PMID: 28932515
- PMCID: PMC5594119
- DOI: 10.21037/jtd.2017.06.134
The J-ALEX trial-is frontline alectinib a new standard of care?
Conflict of interest statement
Conflicts of Interest: The authors have no conflicts of interest to declare.
Comment on
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Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial.Lancet. 2017 Jul 1;390(10089):29-39. doi: 10.1016/S0140-6736(17)30565-2. Epub 2017 May 10. Lancet. 2017. PMID: 28501140 Clinical Trial.
References
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- 1. National Comprehensive Cancer Network. Non-Small Cell Lung Cancer (Version 5. 2017). Available online: https://www.nccn.org/professionals/physician_gls/pdf/nscl.pdf
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- Felip E, Bauer T, Solomon B, et al. Safety and efficacy of lorlatinib (PF-06463922) in patients with advanced ALK+ or ROS1+ non-small-cell lung cancer (NSCLC). J Thorac Oncol 2017;12:S383-4. 10.1016/j.jtho.2016.11.433 - DOI
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- Reckamp KL, Wakelee HA, Patel S, et al. CNS activity of ensartinib in ALK+ non-small cell lung cancer (NSCLC) patients (pts). J Thorac Oncol 2017;28: ii28-ii51.
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