Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Aug;9(8):2660-2669.
doi: 10.21037/jtd.2017.07.82.

Donors after cardiocirculatory death and lung transplantation

Ilhan Inci  1
Affiliations
Review

Donors after cardiocirculatory death and lung transplantation

Ilhan Inci. J Thorac Dis. 2017 Aug.

Abstract

The number of patients actively awaiting lung transplantation (LTx) is more than the number of suitable donor lungs. The percentage of lung retrieval rate is lower when compared to other solid organs. The use of lungs from donation after cardiocirculatory death (DCD) donors is one of the options to avoid organ shortage in LTx. After extensive experimental research, clinical application of DCD donation is becoming wider. The results from most of the centers show at least equal survival rate compared to donors from brain death. This review paper will summarize experimental background and clinical experience from DCD donors.

Keywords: Donation after cardiocirculatory death (DCD); lung; lung transplantation (LTx); survival.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Schematic presentation of the time points and intervals for cDCD donors recommended by ISHLT DCD Working Group (14).
See this image and copyright information in PMC

References

    1. Van Raemdonck DE, Rega FR, Neyrinck AP, et al. Non-heart-beating donors. Semin Thorac Cardiovasc Surg 2004;16:309-21. 10.1053/j.semtcvs.2004.09.014 - DOI - PubMed
    1. Egan TM. Non-heart-beating donors in thoracic transplantation. J Heart Lung Transplant 2004;23:3-10. 10.1016/S1053-2498(02)00658-7 - DOI - PubMed
    1. Thuong M, Ruiz A, Evrard P, et al. New classification of donation after circulatory death donors definitions and terminology. Transpl Int 2016;29:749-59. 10.1111/tri.12776 - DOI - PubMed
    1. Reeb J, Keshavjee S, Cypel M. Successful lung transplantation from a donation after cardiocirculatory death donor taking more than 120 minutes to cardiac arrest after withdrawal of life support therapies. J Heart Lung Transplant 2016;35:258-9. 10.1016/j.healun.2015.10.010 - DOI - PubMed
    1. Mooney JJ, Hedlin H, Mohabir PK, et al. Lung Quality and Utilization in Controlled Donation After Circulatory Determination of Death Within the United States. Am J Transplant 2016;16:1207-15. 10.1111/ajt.13599 - DOI - PMC - PubMed

LinkOut - more resources