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Case Reports
. 2017 Sep 8;3(5):422-424.
doi: 10.1016/j.jdcr.2017.06.009. eCollection 2017 Sep.

Successful treatment of hydroxyurea-associated panniculitis and vasculitis with low-dose methotrexate

Sarah Mattessich  1 , Katalin Ferenczi  2 , Jun Lu  2
Affiliations
Case Reports

Successful treatment of hydroxyurea-associated panniculitis and vasculitis with low-dose methotrexate

Sarah Mattessich et al. JAAD Case Rep. .
No abstract available

Keywords: hydroxyurea; methotrexate; panniculitis; vasculitis.

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Figures

Fig 1
Fig 1
Clinical presentations of multiple erythematous indurated plaques and subcutaneous nodules on the lower back (A), leg (B), and dorsal foot (C).
Fig 2
Fig 2
Histologic examination. A, Deep dermal and subcutaneous infiltrate. B, Septal thickening and inflammation with lobular spilling of the infiltrate. C, Vessel wall infiltration by inflammatory cells with luminal obliteration and adjacent eosinophil-rich infiltrate. (A, Hematoxylin-eosin stain; original magnifications: A, ×10; B, ×20; C, ×40.)
Fig 3
Fig 3
Complete resolution of vasculitis and panniculitis after low-dose methotrexate treatment.
See this image and copyright information in PMC

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References

    1. Griesshammer M., Gisslinger H., Mesa R. Current and future treatment options for polycythemia vera. Ann Hematol. 2015;94(6):901–910. - PMC - PubMed
    1. Dingli D., Tefferi A. Hydroxyurea: The drug of choice for polycythemia vera and essential thrombocythemia. Curr Hematol Malig Rep. 2006;1(2):69–74. - PubMed
    1. Seidler A.M., Gottlieb A.B. Dermatomyositis induced by drug therapy: a review of case reports. J Am Acad Dermatol. 2008;59(5):872–880. - PubMed
    1. Oh S.T., Lee D.W., Lee J.Y., Cho B.K. Hydroxyurea-induced melanonychia concomitant with a dermatomyositis-like eruption. J Am Acad Dermatol. 2003;49(2):339–341. - PubMed
    1. Young H.S., Khan A.S.A., Kendra J.R., Coulson I.H. The cutaneous side-effects of hydroxyurea. Clin Lab Haematol. 2000;22(4):229–232. - PubMed

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