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Case Reports
. 2017 Sep 8;3(5):425-428.
doi: 10.1016/j.jdcr.2017.06.010. eCollection 2017 Sep.

Palisaded neutrophilic granulomatous dermatitis: Spectrum of histologic findings in a single patient

Affiliations
Case Reports

Palisaded neutrophilic granulomatous dermatitis: Spectrum of histologic findings in a single patient

Jessica E Kalen et al. JAAD Case Rep. .
No abstract available

Keywords: GA, granuloma annulare; PNGD, palisaded neutrophilic granulomatous dermatitis; RA, rheumatoid arthritis; palisaded neutrophilic granulomatous dermatitis; rheumatoid arthritis.

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Figures

Fig 1
Fig 1
A, Erythematous-to-violaceous plaques and nodules on the palmar surfaces, knees, and shins. B, Erythematous plaques on the extensor arms and dorsal hands.
Fig 2
Fig 2
Prominent papillary dermal edema overlying a mixed dermal infiltrate with abundant neutrophils. In isolation, these morphologic findings are strikingly similar to those of neutrophilic dermatoses, such as Sweet syndrome. (Hematoxylin-eosin stain; original magnifications: A, ×40; B, ×100; C, ×200.)
Fig 3
Fig 3
Interstitial and palisading granulomas surround foci of neutrophils with karyorrhectic debris; these features are readily identified as palisaded neutrophilic granulomatous dermatitis. (Hematoxylin-eosin stain; original magnifications: A, ×40; B, ×100; C, ×200.)
Fig 4
Fig 4
Palisading histiocytes surround degenerating collagen; increased dermal mucin and solar elastosis are also present. These morphologic findings closely resemble GA. (Hematoxylin-eosin stain; original magnifications: A, ×40; B, ×100; C, ×200.)

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