[Update on anti-N-methyl-D-aspartate receptor encephalitis]
- PMID: 28932896
- DOI: 10.1007/s00115-017-0405-0
[Update on anti-N-methyl-D-aspartate receptor encephalitis]
Abstract
Autoimmune encephalitis is a group of autoimmune inflammatory disorders affecting both grey and white matter of the central nervous system. Encephalitis with autoantibodies against the N‑methyl-D-aspartate receptor (NMDA-R) is the most frequent autoimmune encephalitis syndrome presenting with a characteristic sequence of psychiatric and neurological symptoms. Treatment necessitates a close interdisciplinary cooperation. This article provides an update on the current knowledge on diagnostic standards, pathogenesis, and treatment strategies for anti-NMDA-R encephalitis from psychiatric and neurological perspectives.
Keywords: Autoantibody-mediated encephalitis; Herpes simplex encephalitis; Neurological symptoms; Ovarian teratoma; Psychiatric symptoms.
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