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Editorial
. 2017 Oct 18;16(20):1849-1850.
doi: 10.1080/15384101.2017.1372523. Epub 2017 Sep 21.

PWWP2A: A novel mitosis link?

Stephanie Link  1   2 , Sandra B Hake  2
Affiliations
Editorial

PWWP2A: A novel mitosis link?

Stephanie Link et al. Cell Cycle. .
No abstract available

Keywords: H2A.Z,; PWWP2A,; mitosis.

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Figures

Figure 1.
Figure 1.
Consequences of PWWP2A depletion on mitosis. Mitosis consists of a series of phases starting from prophase, prometaphase, metaphase, anaphase, telophase (not shown) and cytokinesis. Depletion of PWWP2A causes back-and-forth shuffling between prometaphase and metaphase with many cells showing improperly aligned chromosomes at the equatorial plate (B).
See this image and copyright information in PMC

Comment on

  • Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation.
    Pünzeler S, Link S, Wagner G, Keilhauer EC, Kronbeck N, Spitzer RM, Leidescher S, Markaki Y, Mentele E, Regnard C, Schneider K, Takahashi D, Kusakabe M, Vardabasso C, Zink LM, Straub T, Bernstein E, Harata M, Leonhardt H, Mann M, Rupp RA, Hake SB. Pünzeler S, et al. EMBO J. 2017 Aug 1;36(15):2263-2279. doi: 10.15252/embj.201695757. Epub 2017 Jun 23. EMBO J. 2017. PMID: 28645917 Free PMC article.

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