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. 2017 Sep 15;216(suppl_4):S493-S498.
doi: 10.1093/infdis/jix331.

The Global Threat of Animal Influenza Viruses of Zoonotic Concern: Then and Now

Marc-Alain Widdowson  1   2 , Joseph S Bresee  3 , Daniel B Jernigan  3
Affiliations

The Global Threat of Animal Influenza Viruses of Zoonotic Concern: Then and Now

Marc-Alain Widdowson et al. J Infect Dis. .

Abstract

Animal influenza viruses can reassort or mutate to infect and spread sustainably among people and cause a devastating worldwide pandemic. Since the first evidence of human infection with an animal influenza virus, in 1958, 16 different novel, zoonotic influenza A virus subtype groups in 29 countries, Taiwan, and Hong Kong have caused human infections, with differing severity and frequency. The frequency of novel influenza virus detection is increasing, and human infections with influenza A(H5N1) and A(H7N9) viruses are now annual seasonal occurrences in Asia. The study of the epidemiology and virology of animal influenza viruses is key to understanding pandemic risk and informing preparedness. This supplement brings together select recent articles that look at the risk of emergence and transmission of and approaches to prevent novel influenza virus infections.

Keywords: Influenza; global; novel; pandemic; zoonotic.

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Figures

Figure 1.
Figure 1.
A, Number of countries reporting to the Global Influenza Surveillance and Response System, by year, since 2000. B, Total number of seasonal influenza virus–positive specimens reported to the GISRS, by year and by influenza virus type and subtype, since 2000. Abbreviation: A(H1N1)pdm09, 2009 pandemic influenza A(H1N1) virus.
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References

    1. Koen JS. A practical method for field diagnosis of swine disease. Am J Vet Med 1919; 14:468–70.
    1. Zimmer SM, Burke DS. Historical perspective—emergence of influenza A (H1N1) viruses. N Engl J Med 2009; 361:279–85. - PubMed
    1. Kluska V, Macku M, Mensik J. Demonstration of antibodies against swine influenza viruses in man. Cesk Pediatr 1961; 16:408–14. - PubMed
    1. Pawlisch R, Easterday BC, Nelson DB, Skinner HG, Levy ME. Influenza - Wisconsin and Washington, D.C. MMWR Morb Mortal Wkly Rep 1976; 25:593.
    1. Jernigan DB, Cox NJ. Human influenza: one health, one world. In: Webster RG, Monto AS, Braciale TJ, Lamb RA, ed. Textbook of influenza. 2nd ed Hoboken, NJ: John Wiley and Sons, 2013:3–19.

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