Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016;5(5):92-101.

Metabolic Correction in Patients Sample with Diabetes: Clinical Outcomes and Costs Reductions

Affiliations

Metabolic Correction in Patients Sample with Diabetes: Clinical Outcomes and Costs Reductions

Jorge R Miranda-Massari et al. Int J Diabetes Res. 2016.

Abstract

Diabetes is a leading cause of mortality and morbidity worldwide. Diabetes complications produce profound impact on patient's quality of life and represent very significant economic cost to patients, their family, the government and society as a whole. Metabolic correction has been proposed as an efficient method to improve clinical outcomes and reduce costs in diabetes. Metabolic correction is a concept that supports health maintenance and promotes the healing processes by improving the body's biochemical-physiological mechanisms. This is done by helping activate the metabolic enzymes necessary to facilitate key physiological pathways. A group of 50 patients followed a simple metabolic correction strategy based on hydration, diet, and magnesium supplementation during a 6 months period. Outcomes measures included laboratory testing, anthropometric measures and medication use including its related costs. Patients had an average weight loss of 9.4 lbs (↓5.0%) from baseline at month 3 and 12 lbs (↓6.4%) at month 6. Waist circumference decreased on average 3.7 inches (↓9.0%) from baseline at month 3 and had further decrease to 5.5 inches (↓13.4%) from baseline at month 6. Laboratory testing of average triglycerides decreased from a baseline of 156.9 to 116.7 (↓25.6%) at month 3 and maintained a reduction of ↓24.2% by month 6. Total cholesterol concentration decreased from a baseline of 181.1 mg/dL to 173.9 (↓4.0%) in month 3 and to 171.1 (↓5.5%) at month 6. Average HgA1c decreased from baseline of 7.17 to 6.52 (↓9.1%) at month 3 and maintained 6.52 at months 6. The atherogenic index decreased from 4.18 at baseline to 3.85 at month 3 (↓7.9%) and then 3.47 (17.0%) at month 6. Medication use and cost was quantified in various ways. The average baseline monthly diabetes medication cost per patient of $124.10 was reduced to $ 78.23 (↓36.7% reduction) at month 3 and to $62.80 (↓49.4% reduction) at month 6. A simple and well structured metabolic correction program that includes a significant educational component, dietary modifications and dietary supplement intake was able to maintain or improve vital signs, anthopometric and laboratory measurements that correlate with improved clinical diabetes and cardiovascular health. This outcome was achieved while decreasing the use medications at month 3 and 6 at significant cost savings.

Keywords: Cost reduction; Diabetes; Diabetes care cost; Diet; Magnesium; Magnesium supplementation; Metabolic Correction.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Labs and anthropometics over 6 months period in MRT-MD protocol
Figure 2
Figure 2
Atherogenic Index and Glycosilated hemoglobin over 6 months period
Figure 3
Figure 3
Monthly Medication Cost Reduction per patient over 6 month

Similar articles

Cited by

References

    1. WHO. Country and regional data on diabetes. World Health Organization. WHO; 2015. [Retrieved Nov 8, 2015]. from http://www.who.int/diabetes/facts/en/
    1. Hu Frank B. Globalization of Diabetes. Diabetes Care. 2011 Jun;34(6):1249–1257. - PMC - PubMed
    1. Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001 Dec 13;414(6865):782–7. - PubMed
    1. CMS. National Health Expenditure Projections, 2014–24: Spending Growth Faster Than Recent Trends. Health Affairs CMS. 2015 Jul;34(8):1407–1417. - PubMed
    1. WHO Medicine Prices. New WHO report shows that transparency and cooperation help to reduce high prices for new medicines. Copenhagen: WHO; 2015. [Retrieved Nov 8, 2015]. from http://0x9.me/DqJKO.

LinkOut - more resources