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. 2017 Nov;25(11):1903-1909.
doi: 10.1002/oby.21971. Epub 2017 Sep 20.

Objectively Assessed Physical Activity and Weight Loss Maintenance among Individuals Enrolled in a Lifestyle Intervention

Jessica L Unick  1   2 , Sarah A Gaussoin  3 , James O Hill  4 , John M Jakicic  5 , Dale S Bond  1 , Margareta Hellgren  6 , Karen C Johnson  7 , Anne L Peters  8 , Mace Coday  7 , Dalane W Kitzman  3 , Suzette Bossart  4 , Rena R Wing  1 ; Look AHEAD Research Group.
Affiliations

Objectively Assessed Physical Activity and Weight Loss Maintenance among Individuals Enrolled in a Lifestyle Intervention

Jessica L Unick et al. Obesity (Silver Spring). 2017 Nov.

Abstract

Objective: To examine the relationship between objectively assessed moderate-to-vigorous intensity physical activity (MVPA) and 4-year weight loss (WL) and WL maintenance among individuals with diabetes enrolled in the Look AHEAD trial.

Methods: MVPA was measured in a subgroup of lifestyle intervention participants with accelerometry data at baseline and at 1 and 4 years (n = 553; age: 59.7 ± 6.8 y; BMI: 35.5 ± 5.9 kg/m2 ). Minutes per week of bout-related MVPA were calculated (≥ 3 metabolic equivalents, ≥ 10-min bouts), and adherence to the national physical activity (PA) recommendation for WL maintenance (≥ 250 min/wk) was assessed.

Results: Independent of 1-year WL, 4-year MVPA (β = -0.003, SE = 0.002, P = 0.006), but not 1-year MVPA (β = 0.0001, SE = 0.001, P = 0.50), was significantly associated with 4-year WL. Compared with "nonmaintainers" (≥ 10% WL at year 1, but < 10% at year 4; n = 132), WL maintainers (≥ 10% WL at years 1 and 4; n = 103) had higher MVPA at year 1 (253.4 ± 251.8 vs. 163.9 ± 158.2 min/wk, P = 0.002) and year 4 (155.3 ± 180.6 vs. 111.4 ± 154.5 min/wk, P = 0.046). Although 38.8% and 22.3% of WL maintainers engaged in ≥ 250 min/wk at years 1 and 4, respectively, many engaged in < 150 min/wk (year 1: 41%, year 4: 61%).

Conclusions: Higher weekly MVPA is associated with greater long-term WL and weight maintenance; however, many individuals are able to maintain ≥ 10% WL while engaging in little MVPA.

Trial registration: ClinicalTrials.gov NCT00017953.

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Conflict of interest statement

Disclosure: Dr. Hill reports having stock options in Retrofit, a company providing weight management to the public and is also a member of LLC-Shakabuku, which also provides weight management to the public. Dr Peters has served as a consultant and speaker for Boehringer Ingelheim, Eli Lilly and Company, Janssen, Merck, NovoNordisk, and Sanofi. Dr. Jakicic received an honorarium for serving on the Scientific Advisory Board for Weight Watchers International, was the Principal Investigator on a grant to examine the validity of activity monitors awarded to the University of Pittsburgh by Jawbone, Inc., a co-investigator on a grant award to the University of Pittsburgh by HumanScale, a co-investigator on a grant awarded to the University of Pittsburgh by Weight Watchers International. The remaining authors declare no potential conflict of interest.

Figures

Figure 1
Figure 1
a: Percent weight change at 1 year, stratified by 1-year MVPA levels (Aim 1) b: Percent weight change at 4 years, stratified by 4-year MVPA levels (Aim 2) Physical activity categories based upon minutes/week of bout-related MVPA at Year 1 (a) and Year 4 (b). Overall p-value represents a group effect for categorized MVPA. Values with different superscripts indicate that groups are significantly different from one another. a. Percent weight change at 1 year, stratified by 1-year MVPA levels (Aim 1), b. Percent weight change at 4 years, stratified by 4-year MVPA levels (Aim 2)
Figure 2
Figure 2
a: Aim 3: Percentage of participants maintaining or not maintaining weight loss from years 1-4, stratified by MVPA levels at year 1 b: Aim 3: Percentage of participants maintaining or not maintaining weight loss from years 1-4, stratified by MVPA levels at year 4 Maintain: ≥10% weight loss at Year 1 and Year 4; Non-maintain: ≥10% weight loss at Year 1 and <10% weight loss at Year 4. Overall p-value represents whether the distribution of participants falling into the various PA categories differs between weight loss Maintainers and Non-maintainers. * indicates that the percentage of Maintain participants falling within a particular MVPA category is significantly different from the percentage of Non-maintain participants falling into that category. a. Aim 3: Percentage of participants maintaining or not maintaining weight loss from years 1-4, stratified by MVPA levels at year 1, b. Aim 3: Percentage of participants maintaining or not maintaining weight loss from years 1-4, stratified by MVPA levels at year 4
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References

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