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Comment
. 2017 Oct;137(10):2047-2049.
doi: 10.1016/j.jid.2017.07.828.

New Evidence Supporting Cyclosporine Efficacy in Epidermal Necrolysis

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New Evidence Supporting Cyclosporine Efficacy in Epidermal Necrolysis

Jean-Claude Roujeau et al. J Invest Dermatol. 2017 Oct.
Free article

Abstract

Sixty years after its original description by Sir Alan Lyell, epidermal necrolysis (from Stevens-Johnson syndrome to toxic epidermal necrolysis) seems finally amenable to a specific treatment in addition to essential symptomatic measures in specialized settings. A recently published systematic review and an article by Gonzales-Herrada et al. strongly suggest that cyclosporine is effective in reducing the risk of death.

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